Immunoprotective Effect of Cocos nucifera Oil on Sheep Red Blood Cell-Induced Immunocompromised Rats
نویسندگان
چکیده
The aim of this study is to investigate the immunoprotective effects cold-pressed coconut oil in immunocompromised rat. Standard procedure was used perform research work with a modified method. effect immunomodulatory properties evaluated after challenging animals 0.3 ml sheep red blood cells (SRBCs) intraperitoneally and further treated graded doses (0.25, 0.5 1.0 ml/kg i.p) extract for 21 days. hematological, CD4, CD8 biochemical histopathological analysis were evaluated. Result obtained from showed significant increase hematological indexes (WBC: 11.70; LYM: 9.9 GRAN: 8.0 HGB: 15.57) across groups, but majorly at lowest dose (0.25 ml/kg). More so CD4 Count specifically 0.25 (7.763 7.830). Anti-oxidant property had reduction malondialdehyde an increased antioxidant enzymes (SOD, CAT GPx) when compared untreated control. body weight groups Liver function test (ALT, AST ALP) no treatment controls. result reveals normal physiological structure heart, lungs, spleen, liver kidney extract. In conclusion, validated ethnomedicinal plant.
منابع مشابه
the effect of aqueous extract of garlic on formalin-induced pain in male rats
چکیده اثر عصاره آبی سیر بر درد ناشی از آزمون فرمالین در موش صحرایی نر به کوشش نرگس اسکندری روزبهانی زمینه و هدف: گیاه سیر از خانواده لیلیاسه و گونهallium sativum بومی آسیای میانه بوده و از دوران ،باستان تاکنون به خواص درمانی متفاوت آن مثل: کاهندگی قندخون، کلسترول خون، فشار خون، اثرات مفیدآن بر دستگاه قلبی عروقی و بیماریهای انعقادی خون، اثرات آنتی اکسیداتیو، درمان بیماریهای تنفسی وگوارشی، ا...
15 صفحه اولEffect of Ethanolic Extract of Coconut (Cocos nucifera) on Aspirin-induced Gastric Ulcer in Albino Rats
Statement of problem: Aspirin is extensively used as an analgesic, antipyretic, anti-thrombotic and antiinflammatory drug. It is safe in therapeutic doses but it is toxic in over dosage or in chronic injudicious use, when it causes acute or chronic toxicity respectively. Acute toxicity causes gastric ulceration and bleeding. Gastric ulcer developed when the imbalance occurs between aggressive a...
متن کاملAnti-inflammatory and Anti-ulcerogenic Effect of Ethanol Extract of Coconut (cocos Nucifera) on Experimental Rats
متن کامل
Biochemical Evaluation of Antidiabetic Activity of Cocos nucifera Flowers in STZ Induced Diabetic Rats
Diabetes mellitus is a chronic metabolic disorder of multiple aetiologies resulting in drastic elevation of blood glucose under both fasting and postprandial conditions, which leads to multiple complications. Currently available drugs are unsuccessful for the treatment of diabetes due to their undesirable side effects Hence, search for novel drugs, especially from plant origin continues. Cocos ...
متن کاملEffect of Thyroid Dysfunctions on Blood Cell Count and Red Blood Cell Indice
Abstract Background Thyroid hormones have a crucial role in metabolism and proliferation of blood cells. Thyroid dysfunction induces different effects on blood cells such as anemia, erythrocytosis leukopenia, thrombocytopenia, and in rare cases causes’ pancytopenia. It also alter RBC indices include MCV, MCH, MCHC and RDW. Thus this study attempted to evaluate effect of hypo & hyperthyroi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Biology, Medicine & Natural Product Chemistry
سال: 2023
ISSN: ['2089-6514', '2540-9328']
DOI: https://doi.org/10.14421/biomedich.2023.121.159-169